Exploring the interaction of influenza A subtypes H1N1 and H3N2 based on an evolution-driven transmission model

نویسندگان

چکیده

Two influenza A subtypes (H1N1 and H3N2) co-circulate pose a serious disease burden globally. It is unclear about the extent of cross-protection between these two as well impact on dynamics. Based an evolution-driven mathematical transmission model, interaction H1N1 H3N2 was explored based monthly incidence data in USA from years 2012 to 2019. The results showed that significant exists. Besides, for much stronger than other way around. also show has substantial influence epidemics. model validated Germany, Austria Norway. forecasting framework proposed with feasible accuracy both retrospective prospective forecasts USA. Our findings quantify highlight importance co-circulating seasonal H3N2.

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ژورنال

عنوان ژورنال: Nonlinear Dynamics

سال: 2022

ISSN: ['1573-269X', '0924-090X']

DOI: https://doi.org/10.1007/s11071-022-07661-7